Professor James B. Rowe
- Professor of Cognitive Neurology, University of Cambridge
- Programme Leader, MRC Cognition and Brain Sciences Unit, University of Cambridge
- Cambridge University Hospitals Trust co-lead for Dementia and Neurodegenerative Disorders Theme
- Honorary Consultant Neurologist, Addenbrooke’s Hospital, Cambridge
- Affiliated Professor of Clinical Neuroscience, University of Copenhagen
- Wellcome Trust Senior Fellow
I am both a neuroscientist and a cognitive neurologist. My early training in Medical Sciences and Experimental Psychology (1st class hons.) began at Downing College at the University of Cambridge (1988-1991), followed by Magdalen College at the University of Oxford (1991-1994) and a PhD at the Functional Imaging Laboratory of the Wellcome Department of Cognitive Neurology (1998-2001), supervised by Professor Richard Frackowiak and Professor Dick Passingham. My PhD focused on the neural mechanisms of response selection and attention to action, in health and Parkinson’s disease, using human neuroimaging techniques, such as positron emission tomography, functional magnetic resonance imaging (fMRI), and repetitive transcranial magnetic stimulation (TMS).
After completing my PhD I undertook full time clinical specialist training in neurology for four years. During my clinical training I continued research, including UK and international collaborations on the interactions within cortical and subcortical neural networks. My Wellcome Trust Intermediate Research Fellowship (2005-2009) enabled me to develop further research methodologies (including magnetoencephalography), clinical experience with Frontotemporal dementia, and the theoretical foundations of his later research program. In 2009, I became a Wellcome Trust Senior Research Fellow in Clinical Science.
In 2015, I was appointed as the Professor of Cognitive Neurology at the University of Cambridge and an affiliated Professor of Clinical Neuroscience at the University of Copenhagen in Denmark. My scientific work has been published in more than 160 high-ranking peer-reviewed articles including Science, Brain, Nature Communications, and Neurology.
I am an active consultant neurologist, leading regional specialist clinics for patients with early dementia, frontotemporal dementia, Progressive Supranuclear Palsy, and other ‘tauopathies’, and I am a consultant in the Cambridge Memory Clinic.
I lead clinical services for Disorders of Movement and Cognition (DMC) (for patients with Progressive Supranuclear Palsy (PSP), Corticobasal degeneration (CBD), atypical disorders) and the Early-onset Dementia Clinic (EDC) (for patients with Frontotemporal dementia (FTD)) at the Cambridge University Hospitals NHS Trust (Addenbrooke’s Hospital).
See the Cambridge Centre for Frontotemporal Dementia and Related Disorders for further information.
Our research interests can be divided into cognitive systems and clinical domains. These interect in our translational science program towards better diagnostics and improved therapies, within the NIHR Cambridge Biomedical Research Centre.
The cognitive systems’ research concerns the experience and regulation of voluntary behaviours, including the neural mechanisms by which we select, change, inhibit and ‘own’ our actions. This work uses fMRI and MEG to study anatomical networks including prefrontal cortex, striatum and parietal cortex. It is supported by my Wellcome Trust Senior Research Fellowship, an MRC program, the McDonnell Foundation Scholar Award and project grants.
The clinical research program studies the effects of FTD, dementia and PSP/CBD on the brain including: the mechanisms by which diseases affect cognition through selectively vulnerable brain networks; the impact of disease on functional brain networks; the ability of drug treatments to improve the control of cognition and action; and new ways to stratify and monitor patients in clinical trials.
Our clinical research programs are funded by the Wellcome Trust, NIHR, MRC and private donations. They are very collabroative, locally, nationally and internationally – for more information, see the Cambridge Centre for Frontotemporal Dementia and Related Disorders.
In addition to the Department of Clinical Neurosciences, much of my work is carried out at the MRC Cognition and Brain Sciences Unit and in collaboration with the MRC Behavioural Neuroscience Institute within the umbrella of Cambridge Neuroscience.
For a full publication list, please visit my Google Scholar website.
E-mail for research: email@example.com
E-mail for NHS (confidential): firstname.lastname@example.org
Telephone (Merete Bergman, PA): 01223 760676
Professor James B. Rowe
Cambridge Centre for Frontotemporal Dementia and Related Disorders
Department of Clinical Neurosciences, University of Cambridge
Herchel Smith Building, Forvie Site, Robinson Way, Cambridge Biomedical Campus
CB2 0SZ, UK